CHARACTERIZATION OF MESENCHYMAL STEM CELLS FROM WHITE ADIPOSE TISSUE OF Macaca fascicularis
نویسندگان
چکیده
Mesenchymal stem cells (MSC) derived from white adipose tissue are considered to be an appropriate therapeutic candidate for various human diseases due their natural ability maintain homeostasis. They have also been use as a alternative sufficient availability and ease of harvesting. MSC play important role in the process adipogenesis energy metabolism that is directly related pathogenesis degenerative metabolic syndromes. The purpose this study was obtain cultures biopsied three adult males Macaca fascicularis evaluate these qualitatively quantitatively regarding characteristics differentiate. Polymerase chain reaction (PCR) used confirm expression mesenchymal cell-specific gene markers, specific growth medium differentiate into adipocytes, chondrocytes, osteocytes. results obtained showed culture M. WAT had fibroblast-like morphology with spindle shape. markers CD73, CD90 CD105, were expressed. able Based on results, found potential source MSC.
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ژورنال
عنوان ژورنال: Jurnal Kedokteran Hewan
سال: 2021
ISSN: ['1978-225X', '2502-5600']
DOI: https://doi.org/10.21157/j.ked.hewan.v15i4.18203